PAK up your troubles
نویسندگان
چکیده
منابع مشابه
PAK-in' Up cGMP for the Move
Although guanylyl cyclases have been implicated in cell migration, how they are activated to promote cell motility is unknown. In this issue, report direct communication between guanylyl cyclases and the Rac-p21-activated kinase (PAK) signaling pathway--which is essential for cell migration--to promote cell motility, through allosteric activation of guanylyl cyclases by autophosphorylated PAK.
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2006
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn1874